Ciprofloxacin in Polyethylene Glycol-Coated Liposomes: Efficacy in Rat Models of Acute or Chronic Pseudomonas aeruginosa Infection

In a previous study in experimental Klebsiella pneumoniae pneumonia, the therapeutic potential of ciprofloxacin was significantly improved by encapsulation in polyethylene glycol-coated (“pegylated”) long-circulating (STEALTH) liposomes. Pegylated liposomal ciprofloxacin in high doses was nontoxic a...

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Dades bibliogràfiques
Autors principals: Bakker-Woudenberg, Irma A. J. M., ten Kate, Marian T., Guo, Luke, Working, Peter, Mouton, Johan W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC127349/
https://ncbi.nlm.nih.gov/pubmed/12121935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2575-2581.2002
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