Ciprofloxacin in Polyethylene Glycol-Coated Liposomes: Efficacy in Rat Models of Acute or Chronic Pseudomonas aeruginosa Infection

In a previous study in experimental Klebsiella pneumoniae pneumonia, the therapeutic potential of ciprofloxacin was significantly improved by encapsulation in polyethylene glycol-coated (“pegylated”) long-circulating (STEALTH) liposomes. Pegylated liposomal ciprofloxacin in high doses was nontoxic a...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Bakker-Woudenberg, Irma A. J. M., ten Kate, Marian T., Guo, Luke, Working, Peter, Mouton, Johan W.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Experimental Therapeutics
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121935/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2575-2581.2002
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