Quinolone Resistance in Staphylococci: Activities of New Nonfluorinated Quinolones against Molecular Targets in Whole Cells and Clinical Isolates

The activity of three new, 8-methoxy-nonfluorinated quinolones (NFQs) against multiple-drug-resistant staphylococci was investigated. First, using Staphylococcus aureus strains containing point mutations in the serine 84–80 hot spots of the target genes (gyrA and grlA), cell growth inhibition potenc...

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Main Authors: Roychoudhury, Siddhartha, Catrenich, Carl E., McIntosh, Eric J., McKeever, Helana D., Makin, Kelly M., Koenigs, Paula M., Ledoussal, Benoit
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC90433/
https://ncbi.nlm.nih.gov/pubmed/11257024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1115-1120.2001
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