In Vitro Resistance Development to Nemonoxacin in Streptococcus pneumoniae: A Unique Profile for a Novel Nonfluorinated Quinolone

Selection of resistant strains in Streptococcus pneumoniae was studied in vitro with nemonoxacin, a novel nonfluorinated quinolone (NFQ), in comparison with quinolone benchmarks, ciprofloxacin, garenoxacin, and gatifloxacin. In stepwise resistance selection studies, a 256-fold loss of potency was ob...

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Detalles Bibliográficos
Publicado en:Microb Drug Resist
Main Authors: Roychoudhury, Siddhartha, Makin, Kelly, Twinem, Tracy, Leunk, Robert, Hsu, Ming Chu
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2016
Assuntos:
Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073217/
https://ncbi.nlm.nih.gov/pubmed/27267788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mdr.2016.0021
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