Amino Acid Repetitions in the Dihydropteroate Synthase of Streptococcus pneumoniae Lead to Sulfonamide Resistance with Limited Effects on Substrate K(m)

Sulfonamide resistance in Streptococcus pneumoniae is due to changes in the chromosomal folP (sulA) gene coding for dihydropteroate synthase (DHPS). The first reported laboratory-selected sulfonamide-resistant S. pneumoniae isolate had a 6-bp repetition, the sul-d mutation, leading to a repetition o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Haasum, Ylva, Ström, Katrin, Wehelie, Rahma, Luna, Vicki, Roberts, Marilyn C., Maskell, Jeffrey P., Hall, Lucinda M. C., Swedberg, Göte
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90378/
https://ncbi.nlm.nih.gov/pubmed/11181365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.805-809.2001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados