Streptococcus pneumoniae Response to Repeated Moxifloxacin or Levofloxacin Exposure in a Rabbit Tissue Cage Model

The role of moxifloxacin and levofloxacin pharmacokinetics (PK) in antimicrobial efficacy and in the selection of fluoroquinolone-resistant Streptococcus pneumoniae strains was investigated using the rabbit tissue cage abscess model. A rabbit tissue cage was created by insertion of sterile Wiffle ba...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Xuan, Dawei, Zhong, Mingkang, Mattoes, Holly, Bui, Khanh Q., McNabb, Jocarol, Nicolau, David P., Quintiliani, Richard, Nightingale, Charles H.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Materias:	Experimental Therapeutics
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90376/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181363/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.794-799.2001
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