Streptococcus pneumoniae Response to Repeated Moxifloxacin or Levofloxacin Exposure in a Rabbit Tissue Cage Model

The role of moxifloxacin and levofloxacin pharmacokinetics (PK) in antimicrobial efficacy and in the selection of fluoroquinolone-resistant Streptococcus pneumoniae strains was investigated using the rabbit tissue cage abscess model. A rabbit tissue cage was created by insertion of sterile Wiffle ba...

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Detalhes bibliográficos
Main Authors: Xuan, Dawei, Zhong, Mingkang, Mattoes, Holly, Bui, Khanh Q., McNabb, Jocarol, Nicolau, David P., Quintiliani, Richard, Nightingale, Charles H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90376/
https://ncbi.nlm.nih.gov/pubmed/11181363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.794-799.2001
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