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Inhibition of Cytochrome P450 (CYP450) Isoforms by Isoniazid: Potent Inhibition of CYP2C19 and CYP3A

Isoniazid (INH) remains the most safe and cost-effective drug for the treatment and prophylaxis of tuberculosis. The use of INH has increased over the past years, largely as a result of the coepidemic of human immunodeficiency virus infection. It is frequently given chronically to critically ill pat...

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Hlavní autoři: Desta, Zeruesenay, Soukhova, Nadia V., Flockhart, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90302/
https://ncbi.nlm.nih.gov/pubmed/11158730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.2.382-392.2001
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