Loading...
Mechanism of Action of 1-β-d-2,6-Diaminopurine Dioxolane, a Prodrug of the Human Immunodeficiency Virus Type 1 Inhibitor 1-β-d-Dioxolane Guanosine
(−)-β-d-2,6-Diaminopurine dioxolane (DAPD), is a nucleoside reverse transcriptase (RT) inhibitor with activity against human immunodeficiency virus type 1 (HIV-1). DAPD, which was designed as a water-soluble prodrug, is deaminated by adenosine deaminase to give (−)-β-d-dioxolane guanine (DXG). By us...
Na minha lista:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2001
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC90254/ https://ncbi.nlm.nih.gov/pubmed/11120959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.158-165.2001 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|