Mefloquine Pharmacokinetic-Pharmacodynamic Models: Implications for Dosing and Resistance

Antimalarial resistance develops and spreads when spontaneously occurring mutant malaria parasites are selected by concentrations of antimalarial drug which are sufficient to eradicate the more sensitive parasites but not those with the resistance mutation(s). Mefloquine, a slowly eliminated quinoli...

詳細記述

書誌詳細

出版年:	Antimicrob Agents Chemother
主要な著者:	Simpson, Julie A., Watkins, Emmeline R., Price, Ric N., Aarons, Leon, Kyle, Dennis E., White, Nicholas J.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2000
主題:	Pharmacology
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.12.3414-3424.2000
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