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Bioavailability of Praziquantel Increases with Concomitant Administration of Food

In the present study we found that after a single oral dose of 1,800 mg of praziquantel, following a high-lipid diet and a high-carbohydrate diet, the maximum levels in plasma increased 243 and 515% and the area under the plasma concentration curve from 0 to 8 h increased 180 and 271%, respectively.

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Bibliographische Detailangaben
Hauptverfasser: Castro, Nelly, Medina, Roberto, Sotelo, Julio, Jung, Helgi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90177/
https://ncbi.nlm.nih.gov/pubmed/10991886
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