Cloning and Nucleotide Sequence of the DNA Gyrase (gyrA) Gene from Mycoplasma hominis and Characterization of Quinolone-Resistant Mutants Selected In Vitro with Trovafloxacin

We report the cloning and characterization of the gyrA gene of the Mycoplasma hominis DNA gyrase, which was previously shown to be associated with quinolone resistance in this organism. The 2,733-bp gyrA gene encodes a protein of 911 amino acids with a calculated molecular mass of 102.5 kDa. As expe...

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Bibliographic Details
Main Authors: Bébéar, C. M., Grau, O., Charron, A., Renaudin, H., Gruson, D., Bébéar, C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90142/
https://ncbi.nlm.nih.gov/pubmed/10991851
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