Sequencing of Gyrase and Topoisomerase IV Quinolone-Resistance-Determining Regions of Chlamydia trachomatis and Characterization of Quinolone-Resistant Mutants Obtained In Vitro

The L2 reference strain of Chlamydia trachomatis was exposed to subinhibitory concentrations of ofloxacin (0.5 μg/ml) and sparfloxacin (0.015 μg/ml) to select fluoroquinolone-resistant mutants. In this study, two resistant strains were isolated after four rounds of selection. The C. trachomatis muta...

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Autors principals: Dessus-Babus, Sophie, Bébéar, Cécile M., Charron, Alain, Bébéar, Christiane, de Barbeyrac, Bertille
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC105861/
https://ncbi.nlm.nih.gov/pubmed/9756744
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