Sequencing of Gyrase and Topoisomerase IV Quinolone-Resistance-Determining Regions of Chlamydia trachomatis and Characterization of Quinolone-Resistant Mutants Obtained In Vitro

The L2 reference strain of Chlamydia trachomatis was exposed to subinhibitory concentrations of ofloxacin (0.5 μg/ml) and sparfloxacin (0.015 μg/ml) to select fluoroquinolone-resistant mutants. In this study, two resistant strains were isolated after four rounds of selection. The C. trachomatis muta...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Dessus-Babus, Sophie, Bébéar, Cécile M., Charron, Alain, Bébéar, Christiane, de Barbeyrac, Bertille
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2474
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