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Cloning and Nucleotide Sequence of the DNA Gyrase (gyrA) Gene from Mycoplasma hominis and Characterization of Quinolone-Resistant Mutants Selected In Vitro with Trovafloxacin

We report the cloning and characterization of the gyrA gene of the Mycoplasma hominis DNA gyrase, which was previously shown to be associated with quinolone resistance in this organism. The 2,733-bp gyrA gene encodes a protein of 911 amino acids with a calculated molecular mass of 102.5 kDa. As expe...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Bébéar, C. M., Grau, O., Charron, A., Renaudin, H., Gruson, D., Bébéar, C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10991851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.10.2719-2727.2000
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