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Comparison of a Rabbit Model of Bacterial Endocarditis and an In Vitro Infection Model with Simulated Endocardial Vegetations

Animal models are commonly used to determine the efficacy of various antimicrobial agents for treatment of bacterial endocarditis. Previously we have utilized an in vitro infection model, which incorporates simulated endocardial vegetations (SEVs) to evaluate the pharmacodynamics of various antibiot...

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Autori principali: Hershberger, Ellie, Coyle, Elizabeth A., Kaatz, Glenn W., Zervos, Marcus J., Rybak, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC89986/
https://ncbi.nlm.nih.gov/pubmed/10858355
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