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Comparison of a Rabbit Model of Bacterial Endocarditis and an In Vitro Infection Model with Simulated Endocardial Vegetations

Animal models are commonly used to determine the efficacy of various antimicrobial agents for treatment of bacterial endocarditis. Previously we have utilized an in vitro infection model, which incorporates simulated endocardial vegetations (SEVs) to evaluate the pharmacodynamics of various antibiot...

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Detalhes bibliográficos
Main Authors: Hershberger, Ellie, Coyle, Elizabeth A., Kaatz, Glenn W., Zervos, Marcus J., Rybak, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89986/
https://ncbi.nlm.nih.gov/pubmed/10858355
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