Daptomycin Activity against Staphylococcus aureus following Vancomycin Exposure in an In Vitro Pharmacodynamic Model with Simulated Endocardial Vegetations

Recently, the emergence of reduced susceptibility to daptomycin has been linked to the reduced vancomycin susceptibility that occurs after vancomycin exposure in Staphylococcus aureus in vivo and in vitro. This study evaluated this propensity in clinical isolates of S. aureus using an in vitro pharm...

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Main Authors: Rose, Warren E., Leonard, Steven N., Sakoulas, George, Kaatz, Glenn W., Zervos, Marcus J., Sheth, Anjly, Carpenter, Christopher F., Rybak, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258488/
https://ncbi.nlm.nih.gov/pubmed/17999971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00869-07
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