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Effect of Zidovudine on the Primary Cytolytic T-Lymphocyte Response and T-Cell Effector Function

Azidothymidine (AZT) and other nucleoside analogues, used to treat AIDS, can cause severe clinical side effects and are suspected of suppressing immune cell proliferation and effector immune cell function. The purpose of the present study was to quantitatively measure the effects of AZT on cytotoxic...

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Hlavní autoři: Francke, Sabine, Orosz, Charles G., Hayes, Kathleen A., Mathes, Lawrence E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC89982/
https://ncbi.nlm.nih.gov/pubmed/10858351
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