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Effect of Zidovudine on the Primary Cytolytic T-Lymphocyte Response and T-Cell Effector Function

Azidothymidine (AZT) and other nucleoside analogues, used to treat AIDS, can cause severe clinical side effects and are suspected of suppressing immune cell proliferation and effector immune cell function. The purpose of the present study was to quantitatively measure the effects of AZT on cytotoxic...

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Detalhes bibliográficos
Main Authors: Francke, Sabine, Orosz, Charles G., Hayes, Kathleen A., Mathes, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89982/
https://ncbi.nlm.nih.gov/pubmed/10858351
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