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Loss of Effector Function of Human Cytolytic T Lymphocytes Is Accompanied by Major Alterations in N- and O-Glycosylation

Most human tumors are not eliminated by the immune system, and therapeutic vaccination shows poor results, a fact that can be explained at least partially by an immunosuppressive tumor microenvironment that is abundant in galectin-3. On cytolytic T lymphocyte (CTL) clones, maintained in culture by r...

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Hlavní autoři: Antonopoulos, Aristotelis, Demotte, Nathalie, Stroobant, Vincent, Haslam, Stuart M., van der Bruggen, Pierre, Dell, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322850/
https://ncbi.nlm.nih.gov/pubmed/22334653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320820
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