Early Murine T-lymphocyte Activation Is Accompanied by a Switch from N-Glycolyl- to N-Acetyl-neuraminic Acid and Generation of Ligands for Siglec-E

It is well established that murine T-lymphocyte activation is accompanied by major changes in cell-surface sialylation, potentially influencing interactions with sialic acid-binding immunoglobulin-like lectins (siglecs). In the present study, we analyzed early activation of murine CD4+ and CD8+ T-ly...

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Bibliographic Details
Main Authors: Redelinghuys, Pierre, Antonopoulos, Aristotelis, Liu, Yan, Campanero-Rhodes, Maria A., McKenzie, Emma, Haslam, Stuart M., Dell, Anne, Feizi, Ten, Crocker, Paul R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186437/
https://ncbi.nlm.nih.gov/pubmed/21835922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243410
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