Efficacies of Sordarin Derivatives GM193663, GM211676, and GM237354 in a Murine Model of Systemic Coccidioidomycosis

Sordarin derivatives (Glaxo Wellcome) are a new class of compounds that selectively inhibit fungal protein synthesis and have a broad spectrum of activity. Systemic coccidioidomycosis was established in female CD-1 mice infected with Coccidioides immitis, and therapy was begun on day 4 with either G...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Clemons, Karl V., Stevens, David A.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Experimental Therapeutics
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858347/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.7.1874-1877.2000
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