Disposition of Intravenous Pyrimethamine in Healthy Volunteers

A proportion of patients with AIDS and toxoplasmic encephalitis (TE) sustain low plasma pyrimethamine concentrations during oral treatment, possibly because of incomplete and variable bioavailability. We wanted to develop a safe, practicable intravenous (i.v.) formulation of pyrimethamine and charac...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Almond, D. S., Szwandt, I. S. F., Edwards, G., Lee, M. G., Winstanley, P. A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.6.1691-1693.2000
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