Disposition of Intravenous Pyrimethamine in Healthy Volunteers

A proportion of patients with AIDS and toxoplasmic encephalitis (TE) sustain low plasma pyrimethamine concentrations during oral treatment, possibly because of incomplete and variable bioavailability. We wanted to develop a safe, practicable intravenous (i.v.) formulation of pyrimethamine and charac...

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Bibliografski detalji

Izdano u:	Antimicrob Agents Chemother
Glavni autori:	Almond, D. S., Szwandt, I. S. F., Edwards, G., Lee, M. G., Winstanley, P. A.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2000
Teme:	Pharmacology
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.6.1691-1693.2000
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