Evernimicin (SCH27899) Inhibits both Translation and 50S Ribosomal Subunit Formation in Staphylococcus aureus Cells

The effects of the everninomicin antibiotic evernimicin (SCH27899) on growing Staphylococcus aureus cells were investigated. Cellular growth rates and viable cell numbers decreased with increasing antibiotic concentrations. The rate of protein synthesis, measured as (35)S-amino acid incorporation, d...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Champney, W. Scott, Tober, Craig L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Mechanisms of Action: Physiological Effects
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.6.1413-1417.2000
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