Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria

Evernimicin (SCH 27899) is a new antibiotic with activity against a wide spectrum of gram-positive bacteria and activity against some gram-negative bacteria. Previous metabolic labeling studies indicated that evernimicin specifically inhibited protein synthesis in Staphylococcus aureus. Using a susc...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	McNicholas, Paul M., Najarian, David J., Mann, Paul A., Hesk, David, Hare, Roberta S., Shaw, Karen J., Black, Todd A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Mechanisms of Action: Physiological Effects
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89832/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10770739/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.5.1121-1126.2000
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