Comparative Pharmacodynamics of Gatifloxacin and Ciprofloxacin in an In Vitro Dynamic Model: Prediction of Equiefficient Doses and the Breakpoints of the Area under the Curve/MIC Ratio

To demonstrate the impact of the pharmacokinetics of gatifloxacin (GA) relative to those of ciprofloxacin (CI) on the antimicrobial effect (AME), the killing and regrowth kinetics of two differentially susceptible clinical isolates each of Staphylococcus aureus, Escherichia coli, and Klebsiella pneu...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Vostrov, Sergey N., Kononenko, Olga V., Lubenko, Irene Y., Zinner, Stephen H., Firsov, Alexander A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722485/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.879-884.2000
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