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Non-Target Gene Mutations in the Development of Fluoroquinolone Resistance in Escherichia coli

Mutations in loci other than genes for the target topoisomerases of fluoroquinolones, gyrA and parC, may play a role in the development of fluoroquinolone resistance in Escherichia coli. A series of mutants with increasing resistance to ofloxacin was obtained from an E. coli K-12 strain and five cli...

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Bibliographische Detailangaben
Hauptverfasser: Kern, W. V., Oethinger, M., Jellen-Ritter, A. S., Levy, S. B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89776/
https://ncbi.nlm.nih.gov/pubmed/10722475
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