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Non-Target Gene Mutations in the Development of Fluoroquinolone Resistance in Escherichia coli

Mutations in loci other than genes for the target topoisomerases of fluoroquinolones, gyrA and parC, may play a role in the development of fluoroquinolone resistance in Escherichia coli. A series of mutants with increasing resistance to ofloxacin was obtained from an E. coli K-12 strain and five cli...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Kern, W. V., Oethinger, M., Jellen-Ritter, A. S., Levy, S. B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.814-820.2000
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