Non-Target Gene Mutations in the Development of Fluoroquinolone Resistance in Escherichia coli

Mutations in loci other than genes for the target topoisomerases of fluoroquinolones, gyrA and parC, may play a role in the development of fluoroquinolone resistance in Escherichia coli. A series of mutants with increasing resistance to ofloxacin was obtained from an E. coli K-12 strain and five cli...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Kern, W. V., Oethinger, M., Jellen-Ritter, A. S., Levy, S. B.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2000
Fag:	Mechanisms of Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89776/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722475/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.814-820.2000
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