pncA Mutations as a Major Mechanism of Pyrazinamide Resistance in Mycobacterium tuberculosis: Spread of a Monoresistant Strain in Quebec, Canada

Pyrazinamide (PZA) is an important first-line tuberculosis drug that is part of the currently used short-course tuberculosis chemotherapy. PZA is a prodrug that has to be converted to the active form pyrazinoic acid by pyrazinamidase (PZase) activity, encoded by the pncA gene of Mycobacterium tuberc...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Antimicrob Agents Chemother
Päätekijät:	Cheng, Shao-Ji, Thibert, Louise, Sanchez, Tracy, Heifets, Leonid, Zhang, Ying
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2000
Aiheet:	Mechanisms of Resistance
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681313/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.3.528-532.2000
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!