Involvement of an Active Efflux System in the Natural Resistance of Pseudomonas aeruginosa to Aminoglycosides

A mutant, named 11B, hypersusceptible to aminoglycosides, tetracycline, and erythromycin was isolated after Tn501 insertion mutagenesis of Pseudomonas aeruginosa PAO1. Cloning and sequencing experiments showed that 11B was deficient in an, at that time, unknown active efflux system that contains hom...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Aires, Julio Ramos, Köhler, Thilo, Nikaido, Hiroshi, Plésiat, Patrick
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89534/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10543738/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.11.2624
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