Histatin 3-Mediated Killing of Candida albicans: Effect of Extracellular Salt Concentration on Binding and Internalization

Human saliva contains histidine-rich proteins, histatins, which have antifungal activity in vitro. The mechanism by which histatins are able to kill Candida albicans may have clinical significance but is currently unknown. Using radiolabeled histatin 3, we show that the protein binds to C. albicans...

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Main Authors: Xu, Yanying, Ambudkar, Indu, Yamagishi, Hisako, Swaim, William, Walsh, Thomas J., O’Connell, Brian C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89457/
https://ncbi.nlm.nih.gov/pubmed/10471575
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