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Histatin 3-Mediated Killing of Candida albicans: Effect of Extracellular Salt Concentration on Binding and Internalization

Human saliva contains histidine-rich proteins, histatins, which have antifungal activity in vitro. The mechanism by which histatins are able to kill Candida albicans may have clinical significance but is currently unknown. Using radiolabeled histatin 3, we show that the protein binds to C. albicans...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Yanying, Ambudkar, Indu, Yamagishi, Hisako, Swaim, William, Walsh, Thomas J., O’Connell, Brian C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89457/
https://ncbi.nlm.nih.gov/pubmed/10471575
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