Killing of Candida albicans by Human Salivary Histatin 5 Is Modulated, but Not Determined, by the Potassium Channel TOK1

Salivary histatin 5 (Hst 5), a potent toxin for the human fungal pathogen Candida albicans, induces noncytolytic efflux of cellular ATP, potassium, and magnesium in the absence of cytolysis, implicating these ion movements in the toxin's fungicidal activity. Hst 5 action on Candida resembles, i...

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Bibliographic Details
Main Authors: Baev, Didi, Rivetta, Alberto, Li, Xuewei S., Vylkova, Slavena, Bashi, Esther, Slayman, Clifford L., Edgerton, Mira
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC155775/
https://ncbi.nlm.nih.gov/pubmed/12761106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3251-3260.2003
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