Killing of Candida albicans by Human Salivary Histatin 5 Is Modulated, but Not Determined, by the Potassium Channel TOK1

Salivary histatin 5 (Hst 5), a potent toxin for the human fungal pathogen Candida albicans, induces noncytolytic efflux of cellular ATP, potassium, and magnesium in the absence of cytolysis, implicating these ion movements in the toxin's fungicidal activity. Hst 5 action on Candida resembles, i...

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Bibliografiske detaljer
Main Authors: Baev, Didi, Rivetta, Alberto, Li, Xuewei S., Vylkova, Slavena, Bashi, Esther, Slayman, Clifford L., Edgerton, Mira
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC155775/
https://ncbi.nlm.nih.gov/pubmed/12761106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3251-3260.2003
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