Killing of Candida albicans by Human Salivary Histatin 5 Is Modulated, but Not Determined, by the Potassium Channel TOK1

Salivary histatin 5 (Hst 5), a potent toxin for the human fungal pathogen Candida albicans, induces noncytolytic efflux of cellular ATP, potassium, and magnesium in the absence of cytolysis, implicating these ion movements in the toxin's fungicidal activity. Hst 5 action on Candida resembles, i...

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Autors principals: Baev, Didi, Rivetta, Alberto, Li, Xuewei S., Vylkova, Slavena, Bashi, Esther, Slayman, Clifford L., Edgerton, Mira
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155775/
https://ncbi.nlm.nih.gov/pubmed/12761106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3251-3260.2003
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