Killing of Candida albicans by Human Salivary Histatin 5 Is Modulated, but Not Determined, by the Potassium Channel TOK1

Salivary histatin 5 (Hst 5), a potent toxin for the human fungal pathogen Candida albicans, induces noncytolytic efflux of cellular ATP, potassium, and magnesium in the absence of cytolysis, implicating these ion movements in the toxin's fungicidal activity. Hst 5 action on Candida resembles, i...

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Bibliographische Detailangaben
Hauptverfasser: Baev, Didi, Rivetta, Alberto, Li, Xuewei S., Vylkova, Slavena, Bashi, Esther, Slayman, Clifford L., Edgerton, Mira
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC155775/
https://ncbi.nlm.nih.gov/pubmed/12761106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3251-3260.2003
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