A Novel Injectable Water-Soluble Amphotericin B-Arabinogalactan Conjugate

New, stable, highly water-soluble, nontoxic polysaccharide conjugates of amphotericin B (AmB) are described. AmB was conjugated by a Schiff-base reaction with oxidized arabinogalactan (AG). AG is a highly branched natural polysaccharide with unusual water solubility (70% in water). A high yield of a...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Falk, Rama, Domb, Abraham J., Polacheck, Itzhack
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1999
Matèries:	Experimental Therapeutics
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10428922/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.8.1975
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