A Novel Injectable Water-Soluble Amphotericin B-Arabinogalactan Conjugate
New, stable, highly water-soluble, nontoxic polysaccharide conjugates of amphotericin B (AmB) are described. AmB was conjugated by a Schiff-base reaction with oxidized arabinogalactan (AG). AG is a highly branched natural polysaccharide with unusual water solubility (70% in water). A high yield of a...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10428922/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.8.1975 |
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