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A Novel Injectable Water-Soluble Amphotericin B-Arabinogalactan Conjugate

New, stable, highly water-soluble, nontoxic polysaccharide conjugates of amphotericin B (AmB) are described. AmB was conjugated by a Schiff-base reaction with oxidized arabinogalactan (AG). AG is a highly branched natural polysaccharide with unusual water solubility (70% in water). A high yield of a...

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Detalhes bibliográficos
Main Authors: Falk, Rama, Domb, Abraham J., Polacheck, Itzhack
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89400/
https://ncbi.nlm.nih.gov/pubmed/10428922
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