Efficacy of Gatifloxacin in Experimental Escherichia coli Meningitis

The effectiveness of gatifloxacin therapy (15 mg/kg every 5 h [q5h]) was compared with that of meropenem (75 mg/kg q5h) and cefotaxime (75 mg/kg q5h) therapy in experimental meningitis caused by a β-lactamase-producing strain of Escherichia coli. Gatifloxacin therapy was more rapidly bactericidal th...

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Bibliographic Details
Main Authors: Lutsar, Irja, Friedland, Ian R., Jafri, Hasan S., Wubbel, Loretta, Ng, Winston, Ghaffar, Faryal, McCracken, George H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89371/
https://ncbi.nlm.nih.gov/pubmed/10390250
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