Efficacy of Gatifloxacin in Experimental Escherichia coli Meningitis

The effectiveness of gatifloxacin therapy (15 mg/kg every 5 h [q5h]) was compared with that of meropenem (75 mg/kg q5h) and cefotaxime (75 mg/kg q5h) therapy in experimental meningitis caused by a β-lactamase-producing strain of Escherichia coli. Gatifloxacin therapy was more rapidly bactericidal th...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Lutsar, Irja, Friedland, Ian R., Jafri, Hasan S., Wubbel, Loretta, Ng, Winston, Ghaffar, Faryal, McCracken, George H.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1999
Materias:	Experimental Therapeutics
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89371/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390250/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.7.1805
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