Pharmacodynamics of Vancomycin for the Treatment of Experimental Penicillin- and Cephalosporin-Resistant Pneumococcal Meningitis

With the emergence of β-lactam antibiotic resistance among strains of Streptococcus pneumoniae, vancomycin has assumed an important role in the treatment of bacterial meningitis. Using the rabbit meningitis model, we evaluated the pharmacokinetics and pharmacodynamics of vancomycin in this setting....

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ahmed, Amina, Jafri, Hasan, Lutsar, Irja, McCoig, Cynthia C., Trujillo, Monica, Wubbel, Loretta, Shelton, Sharon, McCracken, George H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10103194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.4.876
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