Resistance to β-Lactam Antibiotics in Pseudomonas aeruginosa Due to Interplay between the MexAB-OprM Efflux Pump and β-Lactamase
We evaluated the roles of the MexAB-OprM efflux pump and β-lactamase in β-lactam resistance in Pseudomonas aeruginosa by constructing OprM-deficient, OprM basal level, and OprM fully expressed mutants from β-lactamase-negative, -inducible, and -overexpressed strains. We conclude that, with the notab...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89266/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1301 |
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