Trovafloxacin in Combination with Vancomycin against Penicillin-Resistant Pneumococci in the Rabbit Meningitis Model

Trovafloxacin, a new fluoroquinolone, produced bactericidal activity (−0.33 ± 0.13 Δlog(10) CFU/ml · h; intravenously [i.v.] administered dose, 15 mg/kg) comparable to that of vancomycin (−0.39 ± 0.18 Δlog(10) CFU/ml · h; i.v. administered dose, 20 mg/kg) in the treatment of experimental meningitis...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Rodoni, Dina, Hänni, Fränzi, Gerber, Cynthia M., Cottagnoud, Marianne, Neftel, Klaus, Täuber, Martin G., Cottagnoud, Philippe
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1999
Subjects:	Experimental Therapeutics
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10103211/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.4.963
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