Trovafloxacin in Combination with Vancomycin against Penicillin-Resistant Pneumococci in the Rabbit Meningitis Model

Trovafloxacin, a new fluoroquinolone, produced bactericidal activity (−0.33 ± 0.13 Δlog(10) CFU/ml · h; intravenously [i.v.] administered dose, 15 mg/kg) comparable to that of vancomycin (−0.39 ± 0.18 Δlog(10) CFU/ml · h; i.v. administered dose, 20 mg/kg) in the treatment of experimental meningitis...

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Bibliografiske detaljer
Main Authors: Rodoni, Dina, Hänni, Fränzi, Gerber, Cynthia M., Cottagnoud, Marianne, Neftel, Klaus, Täuber, Martin G., Cottagnoud, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89237/
https://ncbi.nlm.nih.gov/pubmed/10103211
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