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Genetic Evidence that InhA of Mycobacterium smegmatis Is a Target for Triclosan

Three Mycobacterium smegmatis mutants selected for resistance to triclosan each had a different mutation in InhA, an enoyl reductase involved in fatty acid synthesis. Two expressed some isoniazid resistance. A mutation originally selected on isoniazid also mediated triclosan resistance, as did the w...

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Main Authors: McMurry, Laura M., McDermott, Patrick F., Levy, Stuart B.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC89191/
https://ncbi.nlm.nih.gov/pubmed/10049298
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