Genetic Evidence that InhA of Mycobacterium smegmatis Is a Target for Triclosan

Three Mycobacterium smegmatis mutants selected for resistance to triclosan each had a different mutation in InhA, an enoyl reductase involved in fatty acid synthesis. Two expressed some isoniazid resistance. A mutation originally selected on isoniazid also mediated triclosan resistance, as did the w...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	McMurry, Laura M., McDermott, Patrick F., Levy, Stuart B.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 1999
נושאים:	Mechanisms of Action: Physiological Effects
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89191/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.711
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