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Genetic Evidence that InhA of Mycobacterium smegmatis Is a Target for Triclosan

Three Mycobacterium smegmatis mutants selected for resistance to triclosan each had a different mutation in InhA, an enoyl reductase involved in fatty acid synthesis. Two expressed some isoniazid resistance. A mutation originally selected on isoniazid also mediated triclosan resistance, as did the w...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: McMurry, Laura M., McDermott, Patrick F., Levy, Stuart B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89191/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049298/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.711
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