Declining Concentrations of Dihydroartemisinin in Plasma during 5-Day Oral Treatment with Artesunate for Falciparum Malaria

Six patients with uncomplicated falciparum malaria received artesunate for 5 days. Plasma concentrations of artesunate and dihydroartemisinin were determined by high-performance liquid chromatography with electrochemical detection. The concentrations of dihydroartemisinin in plasma 2 h after a dose...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Khanh, Nguyen Xuan, de Vries, Peter J., Ha, Le Dang, van Boxtel, Chris J., Koopmans, Richard, Kager, Piet A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Pharmacology
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89184/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.690
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